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Oct 19, 2014

U.S. hospitals gird for Ebola panic as flu season looms

NEW YORK (Reuters) – A young woman complaining of abdominal pain and nausea who had traveled to Africa arrived at a Long Island hospital fearful that she had contracted Ebola. She did not have the virus, but the pregnancy test was positive.

The woman had been to South Africa, more than 3,400 miles (5,400 km) from the three West African countries enduring the worst Ebola outbreak on record, and the trip ended six weeks prior, or twice the potential incubation period for Ebola infection.

Oct 15, 2014

St. Jude Medical lowers forecast; shares fall

Oct 15 (Reuters) – Heart device maker St. Jude Medical Inc
on Wednesday forecast fourth-quarter revenue below Wall
Street estimates, citing soft international sales and
unfavorable foreign exchange rates, and its shares fell nearly 4
percent.

The maker of pacemakers, implantable defibrillators,
replacement heart valves and neurological products said it
expects fourth-quarter adjusted profit of $1.02 to $1.04 per
share and revenue of $1.39 billion to $1.47 billion.

Oct 8, 2014

Actavis deal for Allergan would be huge bet on branded drugs

Oct 8 (Reuters) – If Actavis Plc proceeds with a
purchase of Botox maker Allergan Inc for potentially
more than $60 billion, it will represent the biggest bet yet by
one of the traditional generic drugmakers on the upside of
expanding branded medicine holdings.

Reuters reported on Tuesday that Actavis plans to approach
Allergan about a potential merger, providing an alternative to
the hostile pursuit by Valeant Pharmaceuticals International
that Allergan had repeatedly rebuffed.

Oct 7, 2014

Bristol-Myers pulls U.S. marketing application for hep C treatment

NEW YORK, Oct 7 (Reuters) – Bristol-Myers Squibb Co
on Tuesday said it is no longer seeking U.S. approval for an
oral two-drug combination to treat hepatitis C because of
competition from rival drugs that require treatment for half as
long and have shown higher cure rates.

The drugmaker’s shares fell more than 2 percent.

Bristol-Myers’ combination of experimental antiviral drugs
daclatasvir and asunaprevir was intended for patients with the
genotype 1b form of the liver-destroying virus, which is far
less prevalent in the United States than the 1a form.

Oct 1, 2014

Esperion drug succeeds in lowering LDL cholesterol -study

Oct 1 (Reuters) – A new type of experimental cholesterol
fighter being developed by Esperion Therapeutics Inc
lowered LDL levels significantly more than Merck & Co
Inc’s Zetia in a midstage clinical trial, the company
said on Wednesday.

In the 12-week study involving 348 patients with high LDL
cholesterol the Esperion drug, ETC-1002, led to an average 30
percent reduction in levels of the “bad” cholesterol for those
who received a 180 milligram dose and a 27 percent reduction
with a 120 mg dose, according to initial results.

Oct 1, 2014

Loss of smell may be predictor of death in older adults: study

By Bill Berkrot

(Reuters) – Being unable to smell bacon frying may be far more dire than simply missing out on one of life’s pleasures. In older adults, it could be a predictor of increased risk of death within five years.

In a study of more than 3,000 people aged 57 to 85, 39 percent of subjects who failed a simple smelling test died within five years, according to results published on Wednesday in the science journal PLOS ONE.

Sep 27, 2014

Pfizer drug effective in patients with rare lung cancer -study

Sept 27 (Reuters) – Pfizer Inc’s Xalkori, which
treats lung cancer patients with a specific gene mutation,
proved effective in shrinking tumors in those with an even rarer
form of the disease, according to data presented at a medical
meeting on Saturday.

In the study of 50 non-small cell lung cancer patients with
a rearrangement of the ROS1 gene, Xalkori treatment led to
significant tumor shrinkage in 36 of them, or 72 percent, and
halted tumor growth in an additional 9 patients, researchers
reported.

Sep 25, 2014

ValueAct returns to Valeant board, plans to raise stake

Sept 25 (Reuters) – Hedge fund ValueAct Capital said on
Thursday it would return to the board of directors of Valeant
Pharmaceuticals International Inc, which is pursuing a
hostile takeover offer for Allergan Inc, and that it
planned to increase its stake in the company.

Valeant shares rose more than 3 percent.

ValueAct Chief Executive Officer Jeffrey Ubben said in a
statement that once he is on the board, he would work with
Valeant on its $53 billion acquisition of Allergan, a deal whose
certainty he has previously questioned.

Sep 23, 2014

Sigma-Aldrich’s $17 bln buyout seen as boost for lab supplier VWR

Sept 23 (Reuters) – The large premium Germany’s Merck KGaA
agreed to pay in a $17 billion acquisition of
Sigma-Aldrich Corp shines a spotlight on, and
potentially raises the value of, a company Merck discarded a
decade ago.

VWR Corp, a supplier of laboratory chemicals and equipment
with annual sales of about $4.2 billion, is owned by private
equity firm Madison Dearborn Partners. It is gearing up for an
initial public offering after filing with U.S. regulators in
June.

Sep 14, 2014

Abbott dissolving stent has lower angina rate vs metal stent: study

By Bill Berkrot

(Reuters) – Abbott’s Absorb dissolving heart stent proved as safe and effective one year after being placed in a diseased artery as the company’s market-leading Xience drug coated metal stent with a significantly lower rate of chest pain, according to data presented at a medical meeting on Sunday.

Absorb works in the same way as traditional heart stents, propping open arteries that have been cleared of blockages to restore normal blood flow. But unlike metal stents that remain permanently in place, Absorb softens over several months and dissolves in two to three years, allowing the treated artery to regain more normal flexibility to expand and contract.

    • About Bill

      "Based in New York, I primarily cover the pharmaceutical and biotechnology sectors as well as other publicly traded companies involved in health care. Previously covered a wide range of sports for Reuters."
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