In the State Department cables released by Wikileaks and so far reported, the most eye-catching as far as Pakistan is concerned is a row with Washington over nuclear fuel.
According to the New York Times, the cables show:
"A dangerous standoff with Pakistan over nuclear fuel: Since 2007, the United States has mounted a highly secret effort, so far unsuccessful, to remove from a Pakistani research reactor highly enriched uranium that American officials fear could be diverted for use in an illicit nuclear device. In May 2009, Ambassador Anne W. Patterson reported that Pakistan was refusing to schedule a visit by American technical experts because, as a Pakistani official said, “if the local media got word of the fuel removal, ‘they certainly would portray it as the United States taking Pakistan’s nuclear weapons,’ he argued.”
The Pakistan Army is deeply sensitive about any questions on the safety of its nuclear weapons. The country is also often awash with conspiracy theories accusing the Americans of harbouring secret plans to dismantle the nuclear weapons.
That said, the row reported by the NYT appeared to have been about HEU at a nuclear research reactor rather than the weapons themselves, so it may turn out to be less dramatic than it appears. Pakistan's nuclear weapons are considered to be well-guarded although analysts have cited a risk of militants trying to seize nuclear material which they might use to make a dirty bomb. (For a factbox on Pakistan's nuclear weapons, see here).
Of potentially huge significance for Pakistan are cables, reported in The Guardian, saying that Saudi Arabia's King Abdullah has repeatedly urged the United States to attack Iran to destroy its nuclear programme.